Are we effectively treating fungal infections?


Invasive fungal infections – A major cause for concern?

  • Each year, fungal infections are responsible for around 1.4 million deaths worldwide1

  • Despite this, fungal infections are often misunderstood and receive less public awareness compared to diseases caused by bacteria, viruses and parasites

  • Individuals with impaired immune systems, such as cancer and HIV patients, or those who have undergone bone marrow or organ transplants, are most at risk of suffering from an invasive fungal infection2

  • The fungal pathogens that pose the most risk are Candida, Aspergillus, Pneumocystis and Cryptococcus spp.3


  • Candida is ranked 4th among the most common bloodstream infections4

  • Patients who develop Septicaemia caused by Candida have only a 60% chance of surviving, despite the use of antifungal medications5-11

  • Candida is becoming increasingly resistant to first-line and secondline antifungal medications.12 The few available treatment options are expensive and can be toxic to already sick patients13


  • Aspergillus infections are the most common microbial infections in transplant recipients14

  • Aspergillus is associated with high morbidity and a mortality rate of 70%15

Resistance to antifungal medication is becoming an important clinical problem, which threatens to undo many of the health advances of the last 50 years16

  • In the last 20 years, there has been little change in how clinicians diagnose fungal infections

  • This has led to inappropriate prescribing of antifungal medication and increased medical costs17

  • New strategies are desperately required to better treat and diagnose life-threatening fungal infections


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